Publications

Whole-body integration of gene expression and single-cell morphology

Hernando Vergara, Constantin Pape, Kimberly Meechan, Valentyna Zinchenko, Christel Genoud, Adrian Wanner, Kevin Mutemi, Benjamin Titze, Rachel Templin, Paola Bertucci, Oleg Simakov, Wiebke Dürichen, Pedro Machado, Emily Savage, Lothar Schermelleh, Yannick Schwab, Rainer Friedrich, Anna Kreshuk, Christian Tischer, Detlev Arendt

We present a pipeline for the integration of gene expression data with single-cell morphology in whole-body specimens, and apply it to the marine annelid Platynereis dumerilii.

Cell, 2021

Action prediction error: a value-free dopaminergic teaching signal that drives stable learning

Francesca Greenstreet, Hernando Vergara, Sthitapranjya Pati, Laura Schwarz, Matthew Wisdom, Fred Marbach, Yvonne Johansson, Lars Rollik, Theodore Moskovitz, Claudia Clopath, Marcus Stephenson-Jones

We describe a dopaminergic signal in the striatum that encodes action prediction errors, which serve as a value-free teaching signal that supports learning by reinforcing repeated associations.

bioRxiv, 2022